Articles in scientific journals

 

-2004-2005-2006-2007-2008-2009-2010-2011-2012-2013-2014-2015-2016-2017-2018-2019-

2019

  • Huttunen K, Wlodarczyk AJ, Tirkkonen J, Mikkonen S, Täubel M, Krop E, Jacobs J, Pekkanen J, Heederik D, Zock JP, Hyvärinen A, Hirvonen MR, Adams R, Jones T, Zimmermann R, BéruBé K. Oxidative capacity and hemolytic activity of settled dust from moisture-damaged schools. Indoor Air. 2019;00:1–9. https://doi.org/10.1111/ina.12527
  • Miettinen, M, Leskinen, A., Abbaszade, G, Orasche, J., Sainio, M, Mikkonen, S, Koponen, H, Rönkkö, T, Ruusunen, J, Kuuspalo, K, Tiitta, P, Jalava, P, Hao, L., Fang, D., Wang, Q., Gu, C., Zhao, Y., Michalke, B., Schnelle-Kreis, J., Lehtinen, K.E.J., Zimmermann, R., Komppula, M., Jokiniemi, J., Hirvonen, M.-R., Sippula, O. PM2.5 concentration and composition in the urban air of Nanjing, China: Effects of emission control measures applied during the 2014 Youth Olympic Games. Science of the Total Environment Volume 652, 20 February 2019, Pages 1-18

 

 

2018

 

  • Hu L-W, Qian Z, Bloom MS, Nelson EJ, Liu E, Han B, Zhang N, Liu Y, Ma H, Chen D-H, Yang B-Y, Zeng X-W, Chen W, Komppula M, Leskinen A, Hirvonen M-R, Roponen M, Jalava P, Bai Z, Dong G-H. A panel study of airborne particulate matter concentration and impaired cardiopulmonary function in young adults by two different exposure measurement Atmospheric Environment 180: 103-109. 2018
  • Yang M, Chu C, Bloom MS, Li S, Chen G, Heinrich J, Markevych I, Knibbs LD, Bowatte G, Dharmage SC, Komppula M, Leskinen A, Hirvonen MR, Roponen M, Jalava P, Wang SQ, Lin S, Zeng XW, Hu LW, Liu KK, et al.. 2018. Is smaller worse? New insights about associations of PM1 and respiratory health in children and adolescents. ENVIRONMENT INTERNATIONAL 120: 516-524. . 2018
  • Martikainen, M.-V.a, Rönkkö, T.J, Schaub, B.c, Täubel, M., Gu, C., Wong, G.W.K., Li, J., Pekkanen, J., Komppula, M., Hirvonen, M.-R., Jalava, P.I., Roponen, M. Integrating farm and air pollution studies in search for immunoregulatory mechanisms operating in protective and high-risk environments. Pediatric Allergy and ImmunologyVolume 29, Issue 8, December 2018, Pages 815-822
  • Rönkkö, T.J.a, Jalava, P.Ia, Happo, M.S., Kasurinen, S.a, Sippula, O.a, Leskinen, A.b,c, Koponen, H.a, Kuuspalo, K.a, Ruusunen, J.a, Väisänen, O.c, Hao, L.c, Ruuskanen, A.b, Orasche, J.d,e, Fang, D.f, Zhang, L.f, Lehtinen, K.E.J.b,c, Zhao, Y.f, Gu, C.f, Wang, Q.f, Jokiniemi, J.a, Komppula, M.b, Hirvonen, M.-R.a Emissions and atmospheric processes influence the chemical composition and toxicological properties of urban air particulate matter in Nanjing, China(Article)(Open Access) Science of the Total EnvironmentVolume 639, 15 October 2018, Pages 1290-1310
  • Xu, W., Tamarov, K., Fan, L., Granroth, S.f, Rantanen, J.a, Nissinen, T.a, Peräniemi, S.b, Uski, O.c, Hirvonen, M.-R., Lehto, V.-P. Scalable Synthesis of Biodegradable Black Mesoporous Silicon Nanoparticles for Highly Efficient Photothermal Therapy. ACS Applied Materials and InterfacesVolume 10, Issue 28, 18 July 2018, Pages 23529-23538
  • Kasurinen S, Happo, MS, Rönkkö TJ, Orasche J,Jokiniemi J, Kortelainen M, Tissari J, Zimmermann R, Hirvonen M-R, Jalava PI. Differences between co-cultures and monocultures in testing the toxicity of particulate matter derived from log wood and pellet combustion PLoS ONE Open Access Volume 13, Issue 2, February 2018
  • Ihalainen, M, Jalava, P, Ihantola, T, Kasurinen, S, Uski, O, Sippula, O, Hartikainen, A, Tissari, J, Kuuspalo, K, Lähde, A, Hirvonen, M-R, Jokiniemi, J  Design and validation of an air-liquid interface (ALI) exposure device based on thermophoresis. Aerosol Science and Technology 2018
  • Frei R, Ferstl R, Roduit C, Ziegler M, Schiavi E, Barcik W, Rodriguez-Perez N, Wirz OF, Wawrzyniak M, Pugin B, Nehrbass D, Jutel M, Smolinska S, Konieczna P, Bieli C, Loeliger S, Waser M, Pershagen G, Riedler J, Depner M, Schaub B, Genuneit Jl, Renz H, Pekkanen J, Karvonen AM, Dalphin J-C, van Hage M, Doekes G, Akdis M, Braun-Fahrländer C, Akdis CA, von Mutius E, O'Mahony L, Lauener RP, Alfvén T, Alm J, Bergström A, Engstrand L, Rosenlund H, Hakansson N, Lilja G, Nyberg F, Swartz J, Wickman M, Wildhaber J, Möller A,Brunekreef B, Boeve M, Douwes J, Huber M, Gertraud Weiss MM, Schreue M, Michles KB, Sennhauser F, Scheynius A, Hirvonen M-R, Remes S, Roponen M, Tiittanen P, Dalphin M-L, Gisela Buchele VK, Ege M, Kabesch M, Pfefferle P, Loss G, Hyvärinen A., Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers’ children against airway inflammation and colitis Journal of Allergy and Clinical Immunology Volume 141, Issue 1, January 2018, Pages 382-390.e7
  • Delgado-Eckert E, Fuchs O, Kumar N, Pekkanen J, Dalphin JC, Riedler J, Lauener R, Kabesch M, Kupczyk M, Dahlen SE, Mutius EV, Frey U; PASTURE and BIOAIR Study groups (Bitter S, Braun-Fahrländer C, Büchele G, Dalphin ML, Depner M, Doekes G, Ege MJ, Frei R, Genuneit J, Hirvonen MR, Hyvärinen A, Karvonen AM, Kaulek V, Loss G, Pfefferle PI, Remes S, Renz H, Roduit C, Roponen M, Schaub B, Tiittanen P, Middelveld JW, Dahlén B, Gaga M, Siafakas NM, Papi A, Fabbri LM, Joos G, Rabe KF, Johnston SL, Chanez P, Gjormarkaj M, Howarth PH, Niżankowska-Mogilnicka E): Functional phenotypes determined by fluctuation-based clustering of lung function measurements in healthy and asthmatic cohort participants. Thorax. 73(2):107-115, 2018.
  • Karvonen AM, Tischer C, Kirjavainen PV, Roponen M, Hyvärinen A, Illi S, Mustonen K, Pfefferle PI, Renz H, Remes S, Schaub B, von Mutius, E, Pekkanen J: Early age exposure to moisture damage and systemic inflammation markers at the age of 6 years. Indoor Air. Feb; 28(3):450-458, 2018.
  • Roduit C, Frei R, Ferstl R, Loeliger S, Westermann P, Rhyner C, Schiavi E, Barcik W, Rodriguez-Perez N, Wawrzyniak M, Chassard C, Lacroix C, Schmausser-Hechfellner E, Depner M, von Mutius E, Braun-Fahrländer C, Karvonen A, Kirjavainen P, Pekkanen J, Dalphin JC, Riedler J, Akdis C, Lauener R, O'Mahony L; PASTURE/EFRAIM study group (Hyvärinen A, Remes S, Roponen M, Chauveau A, Dalphin ML, Kaulek V, Ege M, Genuneit J, Illi S, Kabesch M, Schaub B, Pfefferle P, Doekes G). High levels of Butyrate and Propionate in early life are associated with protection against atopy. Allergy 2018 doi: 10.1111/all.13660.
  • Gorlanova O, Illi S, Toncheva AA, Usemann J, Latzin P, Kabesch M, Dalphin JC, Lauener R, Pekkanen JR, Von Mutius E, Riedler J, Kuehni CE, Röösli M, Frey U; BILD and PASTURE study groups (Anagnostopoulou P, Fuchs O, Korten I, Müller L, Proietti E, Schmidt A, Hyvärinen A, Karvonen A, Kirjavainen P, Remes S, Roponen M, Chauveau A, Dalphin ML, Kaulek V, Depner M, Ege M, Genuneit J, Loss G, Pfefferle P, Renz H, Schaub B, Braun-Fahrländer C, Frei R, Roduit C, Doekes G). Protective effects of breastfeeding on respiratory symptoms in infants with 17q21 asthma risk variants. Allergy 2018 doi: 10.1111/all.13568. [Epub ahead of print]

2017

  • Martikainen M-V, Keski-Nisula L,Jacupovic H,  Karvonen A, Pekkanen J, Hirvonen M-R, Roponen M. The lack of natural processes of delivery and neonatal intensive care treatment lead to impaired cytokine responses later in life. The American Journal of Reproductive Immunology  77(3) e 12621  Open Access. 2017
  • Zhou, Y., Hu, L.-W., Qian, Z.M., Geiger, S.D., Parrish, K.L., Dharmage, S.C., Campbell, B., Roponen, M., Jalava, P, Hirvonen M-R. , Heinrich, J., Zeng, X.-W., Yang, B.-Y., Qin, X.-D., Lee, Y.L., Dong, G.-H. Interaction effects of polyfluoroalkyl substances and sex steroid hormones on asthma among children. Scientific Reports 7(1),1140, 2017
  • Uski, O., Torvela, T., Sippula, O., Karhunen, T., Koponen, H., Peräniemi, S., Jalava, P., Happo, M., Jokiniemi, J., Hirvonen, M.-R., Lähde, A. In vitro toxicological effects of zinc containing nanoparticles with different physico-chemical properties. Toxicology in Vitro 42, pp. 105-113, 2017
  • Bergroth E, Roponen M, Keski-Nisula L, Remes S, Karvonen AM, Riedler J, Roduit C, von Mutius E, Dalphin J-C, Lauener R, Hirvonen M-R, Genuneit J, Renz H, Pfefferle PI, Blümer N, Krauss-Etschmann S, Schaub B, Pekkanen J and PASTURE study group. Enhanced T helper 1 and 2 cytokine responses at birth associate with lower risk of middle ear infections in infancy. Pediatric Allergy and Immunology, 28(1) , pp.53-59. 2017
  • Hose AJ, Depner M, Illi S, Lau S, Keil T, Wahn U, Fuchs O, Pfefferle PI, Schmaußer-Hechfellner E, Genuneit J, Lauener R, Karvonen AM, Roduit C, Dalphin JC, Riedler J, Pekkanen J, von Mutius E, Ege MJ (MAS: Bauer CP, Forster J, Zepp F, Wahn V, Schuster A, Bergmann RL, Bergmann KE, Reich A, Grabenhenrich L; PASTURE study group members: Schaub B, Loss GJ, Renz H, Kabesch M, Roponen M, Hyvärinen A, Tiittanen P, Remes S, Braun-Fahrländer C, Frei R, Kaulek V, Dalphin ML, Doekes G, Blümer N, Frey U): Latent class analysis reveals clinically relevant atopy phenotypes in two birth cohorts. J Allergy Clin Immunol 139(6):1935-1945, 2017
  • Twardziok M, Schröder PC, Krusche J, Casaca VI, Illi S, Böck A, Loss GJ, Kabesch M, Toncheva AA, Roduit C, Depner M, Genuneit J, Renz H, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Schaub B; PASTURE Study Group:, Hyvärinen A, Karvonen AM, Kirjavainen PV, Remes S, Kaulek V, Dalphin ML, Ege M, Pfefferle PI, Doekes G: Asthmatic farm children show increased CD3+CD8low T-cells compared to non-asthmatic farm children. Clin Immunol. 183:285-292, 2017.
  • Roduit C, Frei R, Depner M, Karvonen AM, Renz H, Braun-Fahrländer C, Schmausser-Hechfellner E, Pekkanen J, Riedler J, Dalphin JC, von Mutius E, Lauener RP; and the PASTURE study group (Hyvärinen A, Kirjavainen P, Remes S, Roponen M, Dalphin ML, Kaulek V, Ege M, Genuneit J, Illi S, Kabesch M, Schaub B, Pfefferle PI, Doekes G): Phenotypes of atopic dermatitis depending on the timing of onset and progression in childhood. JAMA Pediatr 171(7):655-662, 2017.
  • Kasurinen, S., Jalava, P.I., Happo MS, Sippula O, Uski, O., M.S., Koponen H., Orasche J. Zimmerman, R, Jokiniemi, J.,., Hirvonen, M-R. Particulate emissions from the combustion of birch, beech,and spruce logs cause different cytotoxic responses in A549 cells. Environmental Toxicology32 (5),pp 1487-1499  2017
  • Schröder, P.C., Illi, S., Casaca, V.I., Lluis, A., Böck, A., Roduit, C., Depner, M., Frei, R., Genuneit, J.,Pfefferle, P.I.,Roponen, M., Weber, J., Braun-Fahrländer, C., Riedler, J.,Dalphin, J.C., Pekkanen, J., Lauener, R., von Mutius, E., Schaub, B. Hyvärinen, A., Karvonen, A.M., Hirvonen, M.-R., Tiittanen, P., Remes, S., Doekes, G., Kabesch, M.A switch in regulatory T cells through farm exposure during immune maturation in childhood. Allergy: European Journal of Allergy and Clinical Immunology 72(4), pp. 604-615 2017
  • Tirkkonen, J., Täubel, M., Leppänen, H., Peltonen, M., Lindsley, W., Chen, B.T., Hyvärinen, A., Hirvonen, M.-R., Huttunen, K. Toxicity of airborne dust as an indicator of moisture problems in school buildings. Inhalation Toxicology 29(2), pp. 75-81 2017
  • Happo M.S., Hirvonen M.-R. , Kelz J., Brunner T., Obernberger I., Jalava P. I. Particulate emissions from modern and old technology wood combustion induce distinct time dependent patterns of toxicological responses.  Toxicology in Vitro 44, pp. 164-171.2017

 

2016

  • Schröder PC,  Casaca VI, Illi S, Schieck M, Michel S, Böck A, Roduit C, Frei R, Lluis A, Genuneit J, Pfefferle P, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin J-C, Pekkanen J, von Mutius E, Kabesch M, Schaub B, and the PASTURE study group (Hyvärinen A, Karvonen A, Hirvonen MR, Tiittanen P, Remes S, Kaulek V, Dalphin ML, Ege M, Depner M, Loss G, Renz H, Doekes G. IL-33 polymorphisms are associated with increased risk of hay fever and reduced regulatory T cells in a birth cohort Pediatric Allergy and Immunology, 27:687-695, 2016
  • Tirkkonen J, Täubel M, Hirvonen M-R, Leppänen H, Lindsley WG, Chen BT, Hyvärinen A, Huttunen K. Evaluation of sampling methods for toxicological testing of indoor air particulate matter. Inhalation Toxicology. 28 (11), pp. 500-507, 2016 
  • Brick T, Schober Y, Böcking C, Pekkanen J, Genuneit J, Loss G, Dalphin JC, Riedler J, Lauener R, Nockher WA, Renz H, Vaarala O, Braun-Fahrländer C, von Mutius E, Ege MJ, Pfefferle PI; PASTURE study group (Roponen M, Karvonen A, Hyvärinen A, Tiittanen P, Remes S, Dalphin M-L, Kaulek V, Illi S, Depner M, Schaub B, Kabesch M, Frei R, Roduit C, Doekes G): ω-3 fatty acids contribute to the asthma-protective effect of unprocessed cow's milk. J Allergy Clin Immunol. 2016 Jan 11. doi: 10.1016/j.jaci.2015.10.042.
  • Feng M, Yang Z, Pan L, Lai X, Xian M, Huang X, Chen Y, Schröder PC, Roponen M, Schaub B, Wong GWK, Li J: Associations of natural history and environmental factors with asthma among children in rural and urban areas of Guangdong, China. Chest, 149(4): 1030-41,2016.
  • Huttunen K, Tirkkonen J, Taubel M, Leppänen H, Krop E.J. M., Mikkonen S., Pekkanen J., Heederik D., Zock J.P, Hyvärinen A., Hirvonen M-R. Inflammatory potential in relation to the microbial content of settled dust samples collected from moisture-damaged and reference schools: Results of HITEA study.  Indoor Air 2015. In press.
  • Jalava, P.I., Happo, M.S., Huttunen, K., Sillanpää, M., Hillamo, R., Salonen, R.O., Hirvonen, M-R. 2016. Chemical and Microbial Compositions of Urban Air Particles Cause Seasonal Variation of Toxicological Activity. Environmental Toxicology & Pharmacology 40 (2) 375-387.
  • Kasurinen, S., Uski, O., Jalava, P.I., Brunner, T., Happo, M.S., Mäki-Paakkanen, J., Jokiniemi, J., Obernberger, I., Hirvonen, M-R. Toxicological characterization of particulate emissions from biomass fuel alternatives. Aerosol Science and Technology. Volume 50, Issue 1, 2 January 2016, Pages 41-51.
  • Kääriö H, Huttunen K, Karvonen A-M, Schaub B, von Mutius E, Pekkanen J, Hirvonen M-R and Roponen M. Exposure to a farm environment is associated with T helper 1 and regulatory cytokines at age 4.5 years (2015). Clinical & Experimental Allergy. Volume 46, Issue 1, 1 January 2016, Pages 71-77.
  • Kääriö H, Nieminen J, Karvonen AM, Huttunen K, Schröder PC, Vaarala O, von Mutius E, Pfefferle  P I, Schaub B, Pekkanen J, Hirvonen M-R and Roponen M. Circulating dendritic cells, farm exposure and asthma at early age. Scandinavian Journal of Immunology, 83(1):18-25, 2016.
  • Loss GJ, Depner M, Hose AJ, Genuneit J, Karvonen AM, Hyvärinen A, Roduit C, Kabesch M, Lauener R, Pfefferle PI, Pekkanen J, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ; PASTURE study group (Dalphin M-L, Doekes G, Frei R, Hirvonen M-R, Illi S, Kaulek V, Schaub B, Remes S, Renz H, Roponen M, Tiittanen P) 2016. The Early Development of Wheeze: Environmental Determinants and Genetic Susceptibility at 17q21. Am J Respir Crit Care Med, doi: 10.1164/rccm.201507-1493OC.
  • Mustonen K, Karvonen AM, Kirjavainen P, Roponen M, Schaub B, Hyvärinen A, Frey U, Renz H, Pfefferle PI, Genuneit J, Vaarala O, Pekkanen J: Moisture damage in home associates with systemic inflammation in children. Indoor Air, doi: 10.1111/ina.12216. 

 

2015

  • Jalava, P., Wang, Q, Kuuspalo, K, Ruusunen, J., Hao, L., Fang, D, Väisänen,O., Ruuskanen, A., Sippula, O., Happo, M., Uski, O., Kasurinen, S., Torvela, T., Koponen, H., Lehtinen, K.E.J., Komppula, M., Gu, C., Jokiniemi, J., Hirvonen, M.-R. Day and night variation in chemical composition and toxicological responses of size segregated urban air PM samples in a high air pollution situation, Atmospheric Environment (2015) 120, 427-437.
  • Kasurinen, S., Jalava P.I., Tapanainen, M., Uski, O., Happo, M.S., Mäki-Paakkanen, J., Lamberg, H., Koponen, H., Nuutinen, I., Kortelainen, M., Jokiniemi, J., Hirvonen, M-R. (2015) Toxicological effects of particulate emissions – A comparison of oil and wood fuels in small- and medium-scale heating systems. Atmospheric Environment. 103:321-330.
  • Leppänen HK, Täubel M, Roponen M, Vepsäläinen A, Rantakokko P, Pekkanen J, Nevalainen A, von Mutius E, Hyvärinen A: Determinants, reproducibility, and seasonal variation of bacterial cell wall components and viable counts in house dust. Indoor Air 25(3):260-72, 2015.
  • Leskinen, A., Yli-Pirilä, P., Kuuspalo, K., Sippula, O., Jalava, P., Hirvonen, M-R., Jokiniemi, J., Virtanen, A., Komppula, M., Lehtinen, K.E.J. 2015. Characterization and testing of a new environmental chamber. Atmospheric Measurement Techniques 8(6), 2267-2278.
  • Loss G, Depner M, Ulfman LH, van Neerven RJJ, Hose AJ, Genuneit J, Karvonen A, Hyvärinen A, Kaulek V, Roduit C, Weber J, Lauener R, Pfefferle PI, Pekkanen J, Vaarala O, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ, PASTURE study group; M-L Dalphin,  G Doekes,  R Frei, M-R Hirvonen, S Remes, M Roponen, P Tiittanen  S Illi, M Kabesch, H Renz, and B  Schaub. Consumption of unprocessed cow’s milk protects from respiratory infections in the first year of life. J Allergy Clin Immunol, 2015, 135:56-62.
  • Martikainen M-V, Kääriö H, Karvonen A, Schröder P.C., Renz H, Kaulek V, Dalphin JH, Von Mutius E, Schaub B, Pekkanen J, Hirvonen MR, Roponen M.   Farm exposures are associated with lower percentage of circulating myeloid dendritic cell subtype 2 at age 6. Allergy, the European Journal of Allergy and Clinical Immunology, 2015, (10) 1278-1287.
  • Muala, A., Rankin, G., Sehlstedt, M., Unosson, J., Bosson, J.A., Behndig, A., Pourazar, J., Nyström, R., Pettersson, E., Bergwall, C., Westerholm, R., Jalava, P.I., Happo, M.S., Uski, O., Hirvonen, M-R., Kelly, F.J., Mudway, I.S., Blomberg, A., Boman, C., Sandström, T. Acute exposure to wood smoke from incomplete combustion – indications of cytotoxicity. 2015. Particle and Fibre Toxicology 12:33.
  • Nordin EZ, Uski O, Nyström R, Jalava P, Eriksson AC, Genberg J, Roldin P, Bergvall C, Westerholm R, Jokiniemi J, Pagels JH, Boman C, Hirvonen M-R. (2015) Influence of ozone initiated processing on the toxicity of aerosol particles from small scale wood combustion. Atmospheric Environment. 102:282-289.
  • Oeder S, Kanashova T, Sippula O, Sapcariu SC, Streibel T, Dilger M,  Paur HR, Schlager C, Mülhopt M, Diabaté S, Weiss C, Arteaga-Salas JM, Passig M, Stengel B, Rabe R, Harndorf H, Torvela T, Jokiniemi JK, Hirvonen MR, BéruBé KA, Wlodarcyzk AJ, Michalke B, Krebs T, Kelbg M, TiggesbäumkerJ, Karg E, Jakob G, Scholtes S, Schnelle-Kreis J, Lintelmann J, Matuschek G, Sklorz M, Klingbeil S, Orasche J, Richthammer P, Müller L, Elsasser M, Rheda A, Gröger T, Weggler B, Czech B, Rüger C, Abbaszade G, Radischat C, Hiller K, Buters JTM, Dittmar G, Zimmermann R.  Particulate Matter from both Heavy Fuel, Oil and Diesel Fuel Shipping Emissions show Strong Biological Effects on Human Lung Cells at Realistic and Comparable in vitro Exposure Conditions, PLOS ONE, DOI: 10.1371/journal.pone.0126536.
  • Orivuori, L.,http://www.scopus.com/static/images/s.gifMustonen, K., de Goffau, M.C.,Hakala, S.,  Paasela, M.  Roduit, C.,  Dalphin, J.-C.,  Genuneit, J., Lauener, R.,  Riedler, J.,  Weber, J.,  von Mutius, E.,  Pekkanen, J., Harmsen, H.J.M.,  Vaarala, O.,  Hirvonen, M.-R.,Hyvärinen, A.,  Remes, S., Roponen, M., Tiittanen, P.,  Dalphin, M.-L.,  Kaulek, V.,  Depner, M., Ege, M.,  Illi, S., Kabesch, M.,Pfefferle, P.,Renz, H.,  Schaub, B., Doekes, G., Braun-Fahrländer, C., Frei, R., Loss, G. High level of fecal calprotectin at age 2 months as a marker of intestinal inflammation predicts atopic dermatitis and asthma by age 6. Clinical and Experimental Allergy 2015 45:928-939.
  • Rydman E.M, Ilves, M., Vahala E, Vippola M, Lehto M, Kinaret PAS, Pylkkänen L, Happo M, Hirvonen M-R, Grego D, Savolainen K, Wolff H, Alenius H. A single aspiration of rod-like carbon nanotubes induces asbestos-like pulmonary inflammation mediated in part by the IL-1R Toxicol. Sci. kfv112 2015 140(1) 140-155.
  • Sigsgaard. T, Forsberg B,  Annesi-Maesano I, Blomberg A, Bølling, A, Boman, C, Bønløkke J, Brauer M, Bruce N,  Héroux M-E, Hirvonen M-R, Kelly F, Künzli N, Lundbäck B, Moshammer H, Noonan C, Pagels J, Sallsten G, Sculier J-P, Brunekreef B. .Health Impacts of Anthropogenic Biomass Burning in the Developed World. Position paper European Respiratory Journal, 2015 Volume 46, Issue 6, 1 December 2015, Pages 1577-1588.
  • Siponen T, Yli-Tuomi T, Aurela M, Dufva H, Hillamo R,  Hirvonen M-R, Huttunen K, Pekkanen J, Pennanen A, Salonen I, Tiittanen P, Salonen RO, Lanki T. Source-specific fine particulate air pollution and systemic inflammation in ischemic heart disease patients Occup Environ Med 2015; 72: 277-283.
  • Tischer C, Casas L, Wouters IM, Doekes G, Garcia-Esteban R, Gehring U, Hyvärinen A, Oldenwening M, Kerkhof M, Sunyer J, Standl M, Thiering E, Torrent M, Heinrich J; HITEA study group. Early exposure to bio-contaminants and asthma up to 10 years of age: results of the HITEA study. Eur Respir J. 2015 Feb;45(2):328-37. doi: 10.1183/09031936.00060214.
  • Tissari, J, Sippula O, Torvela T, Lamberg H, Leskinen J, Karhunen T, Paukkunen S, Hirvonen M-R, Jokiniemi J. Zinc nanoparticle formation and physicochemical properties in wood combustion - experiments with zinc-doped pellets in a small-scale boiler. Fuel 2015 143, 1: 404-413.
  • Uski, O.  ,Jalava, P.I.  ,Happo, M.S., Torvela, T., Leskinen, J., Mäki-Paakkanen, J., Tissari, J., Sippula, O., Lamberg, H., Jokiniemi, J., Hirvonen, M.-R. Effect of fuel zinc content on toxicological responses of particulate matter from pellet combustion in vitro. Science of the Total Environment 2015, 511, 1:331-340.

2014

  • Depner M, Fuchs O, Genuneit J, Karvonen AM, Hyvärinen A, Kaulek V, Roduit C, Weber J, Schaub B, Lauener R, Kabesch M, Pfefferle PI, Frey U, Pekkanen J, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ; PASTURE Study Group (Bitter S, Büchele G, Dalphin ML, Doekes G, Frei R, Ku C, Hirvonen MR, Loss G, Remes S, Renz H, Roponen M, Tiittanen P). (2014) Clinical and epidemiologic phenotypes of childhood asthma. American Journal of Respiratory and Critical Care Medicine 189(2):129-38.
  • Happo MS, Sippula O, Jalava PI, Rintala H, Leskinen A, Komppula M, Kuuspalo K, Mikkonen S, Lehtinen K, Jokiniemi J, Hirvonen M-R. (2014) Role of microbial and chemical composition in toxicological properties of indoor and outdoor air particulate matter. Particle and Fibre Toxicology. 11:60.
  • Huttunen K, Tiihonen K, Roponen M, Heederik D, Zock JP, Täubel M, Hyvärinen A, Hirvonen MR. (2014) The effect of assay type and sample matrix on detected cytokine concentrations in human blood serum and nasal lavage fluid. Journal of Pharmaceutical and Biomedical Analysis 96:151-5.
  • Leppänen HK, Nevalainen A, Vepsäläinen A, Roponen M, Laine O, von Mutius E, Pekkanen J, and Hyvärinen A. (2014) Determinants, reproducibility and seasonal variation of ergosterol levels in house dust. Indoor Air 24(3):248-59.
  • Leppänen HK, Täubel M, Roponen M, Vepsäläinen A, Rantakokko P, Pekkanen J, Nevalainen A, von Mutius E, Hyvärinen A. (2014) Determinants, reproducibility, and seasonal variation of bacterial cell wall components and viable counts in house dust. Indoor Air. 2015 Jun;25(3):260-72. doi: 10.1111/ina.12141. Epub 2014 Jul 29.
  • Leskinen, J., Tissari, J., Uski, O., Virén, A., Torvela, T., Kaivosoja, T., Lamberg, H., Nuutinen, I., Kettunen, T., Joutsensaari, J., Jalava, PI., Sippula, O., Hirvonen, M-R., Jokiniemi, J. (2014) Fine particle emissions in three different combustion conditions of a woodchip-fired appliance - Particulate physico-chemical properties and induced cell death. Atmospheric Environment. 86:129-139.
  • Lluis, A.*, Depner, M.*, Gaugler, B., Saas, P., Liu, L., Genuneit, J., Pfefferle, P., Roponen, M., Weber, J., Braun-Fahrländer, C., Riedler, J., Lauener, R., Vuitton, D., Dalphin, J-C., Pekkanen, J., von Mutius, E., Schaub, B. and the PASTURE study group (2014) Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood. Journal of Allergy Clinical Immunology. 133(2):551-559.
  • Nwaru BI, Virtanen SM, Alfthan G, Karvonen AM, Genuneit J, Lauener RP, Dalphin JC, Hyvärinen A, Pfefferle P, Riedler J, Weber J, Roduit C, Kaulek V, Braun-Fahrländer C, von Mutius E, Pekkanen J; PASTURE study group (Roponen M, Hirvonen MR, Tiittanen P, Remes S, Dalphin ML, Ege M, Depner M, Schaub B, Büchele G, Renz H, Kabesch M, Bitter S, Loss G, Frei R, Doekes G). (2014) Serum vitamin E concentrations at 1 year and risk of atopy, atopic dermatitis, wheezing, and asthma in childhood: the PASTURE study. Allergy 69(1):87-94.
  • Orivuori L, Loss G, Roduit C, Dalphin J-C, Depner M, Genuneit J, Lauener R, Pekkanen J, Pfefferle P, Riedler J, Roponen M, Weber J, von Mutius E, Braun-Fahrländer C, Vaarala O, and the PASTURE Study Group. (2014) Soluble immunoglobulin A in breast milk is inversely associated with atopic dermatitis at early age: The PASTURE cohort study. Clinical and Experimental Allergy 44(1):102-112.
  • Orivuori L, Mustonen K, Roduit C, Braun-Fahrländer C, Dalphin JC, Genuneit J, Lauener R, Pfefferle P, Riedler J, Weber J, von Mutius E, Pekkanen J, Vaarala O; PASTURE Study Group (Karvonen A, Roponen M, Hirvonen MR, Tiittanen P, Remes S, Kaulek V, Dalphin ML, Buchele G, Ege M, Depner M, Schaub B, Renz H, Kabesch M, Bitter S, Loss G, Frei R, Doekes G). (2014) Immunoglobulin A and immunoglobulin G antibodies against β-lactoglobulin and gliadin at age 1 associate with immunoglobulin E sensitization at age 6. Pediatric Allergy and Immunology 25(4):329-37.
  • Roduit C, Frei R, Depner M, Schaub B, Loss G, Genuneit J, Pfefferle P, Hyvärinen A, Karvonen AM, Riedler J, Dalphin JC, Pekkanen J, von Mutius E, Braun-Fahrländer C, Lauener R; PASTURE study group (Hirvonen MR, Remes S, Roponen M, Tiittanen P, Dalphin ML, Kaulek V, Buchele GB, Ege M, Kabesch M, Renz H, Doekes G). (2014) Increased food diversity in the first year of life is inversely associated with allergic diseases. Journal of Allergy and Clinical Immunology 133(4):1056-64.
  • Torvela T, Uski O, Karhunen T, Lähde A, Jalava P, Sippula O, Tissari J, Hirvonen M-R, Jokiniemi J. (2014) Reference particles for toxicological studies of wood combustion: formation, characteristics and toxicity compared to those of real wood combustion particulate mass. Chemical Research in Toxicology. 27(9): 1516-1527.

 

2013

  • Depner, M., Ege, MJ., Genuneit, J., Pekkanen, J., Roponen, M., Hirvonen, M-R., Dalphin, J-C., Kaulek, V., Krauss-Etschmann, S., Riedler, J., Braun-Fahrländer, C., Roduit, C., Lauener, R., Pfefferle, P., Weber, J., von Mutius, E. and the PASTURE study group (2013) Atopic sensitization in the first year of life. Journal of Allergy Clinical Immunology. 131(3):781-788.
  • Happo MS, Uski O, Jalava PI, Kelz J, Brunner T, Hakulinen P, Mäki-Paakkanen J, Kosma V-M, Jokiniemi J, Obernberger I, Hirvonen M-R. (2013) Pulmonary inflammation and tissue damage in the mouse lung after exposure to PM samples from biomass heating appliances of old and modern technologies. Science of Total Environment.443:256-266.
  • Happo MS, Markkanen A, Markkanen P, Jalava P, Kuuspalo K, Leskinen A, Sippula O, Lehtinen K, Jokiniemi J, Hirvonen MR. (2013) Seasonal variation in the toxicological properties of size-segregated indoor and outdoor air particulate matter. Toxicology In Vitro. 27:1550-1561.
  • Kaivosoja, T., Jalava, PI., Lamberg, H., Viren, A., Tapanainen, M., Torvela, T., Tapper, U., Sippula, O., Tissari, J., Hillamo, R., Hirvonen, MR., Jokiniemi, J. (2013) Comparison of emissions and toxicological properties of fine particles from wood and oil boilers in small (20-25 kW) and medium (5-10 MW) scale. Atmospheric Environment. 77:193-201.
  • Michel, S., Busato, F., Genuneit, J., Pekkanen, J., Dalphin, JC., Riedler, J., Mazaleyrat, N., Weber, J., Karvonen, AM., Hirvonen, MR., Braun-Fahrländer, C., Lauener, R., von Mutius, E., Kabesch, M., Tost, J. and PASTURE study group. (2013) Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy. Allergy. 68(3):355-364.
  • Mustonen, K., Orivuori, L., Keski-Nisula, L., Hyvärinen, A., Pfefferle, PI., Riedler, J., Dalphin, JC., Genuneit, J., Lauener, R., Roduit, C., Braun-Fahrländer, C., Weber, J., Schaub, B., von Mutius, E., Pekkanen, J., Vaarala, O. and PASTURE Study Group (2013) Inflammatory response and IgE sensitization at early age. Pediatric Allergy and Immunology. 24(4):395-401.
  • Orivuori, L., Loss, G., Roduit, C., Dalphin, J-C., Depner, M., Genuneit, J., Lauener, R., Pekkanen, J., Pfefferle, P., Riedler, J., Roponen, M., Weber, J., von Mutius, E., Braun-Fahrländer, C., Vaarala, O., and the PASTURE Study Group (2013) Soluble immunoglobulin A in breast milk is inversely associated with atopic dermatitis at early age: The PASTURE cohort study. Clinical and Experimental Allergy. 44(1):102-112.
  • Roponen, M., Meklin, T., Rintala, H., Hyvärinen, A., Hirvonen, M-R. (2013) Effect of moisture-damage intervention on the immunotoxic potential and microbial content of airborne particles and on occupants' upper airway inflammatory responses. Indoor Air. 23(4):295-302.
  • Sippula O, Rintala H, Happo M, Jalava P, Kuuspalo K, Virén A, Leskinen A, Markkanen A, Komppula M, Markkanen P, Jokiniemi J, Hirvonen M-R. (2013) Characterization of chemical and microbial species from size-segregated indoor and outdoor particulate samples. Aerosol and Air Quality Research. Aerosol and Air Quality Research. 13:1212-1230.

 

2012

  • Haverinen-Shaughnessy, U., Borras-Santos, A., Turunen, M., Zock, JP., Jacobs, J., Krop, EJ., Casas, L., Shaughnessy, R., Täubel, M., Heederik, D., Hyvärinen, A., Pekkanen, J., Nevalainen, A. and HITEA study group (2012) Occurrence of moisture problems in schools in three countries from different climatic regions of Europe based on questionnaires and building inspections - the HITEA study. Indoor Air. 22(6):457-466.
  • Huttunen, K., Siponen, T., Salonen, I., Yli-Tuomi, T., Aurela, M., Dufva, H., Hillamo, R., Linkola, E., Pekkanen, J., Pennanen, A., Peters, A., Salonen, RO., Schneider, A., Tiittanen, P., Hirvonen, MR., Lanki, T. (2012) Low-level exposure to ambient particulate matter is associated with systemic inflammation in ischemic heart disease patients. Environ Res. 116: 44-51.
  • Jalava, PI., Happo, MS., Kelz, J., Brunner, T., Hakulinen, P., Mäki-Paakkanen, J., Jokiniemi, J., Hukkanen, A., Obernberger, I., Hirvonen, M-R. (2012) In vitro toxicological characterization of particulate emissions from residential biomass heating systems based on old and new technology. Atmospheric Environment. 50: 24-35.
  • Jalava, PI., Salonen, RO., Murtonen, T., Aakko-Saksa, P., Markkanen, A., Hakulinen, P., Mäki-Paakkanen, J., Jokiniemi, J., Hirvonen, M-R. (2012) Cytotoxic and inflammatory properties of emission particles from fossil- and biodiesel-fueled Euro IV- heavy diesel engine. Particle and Fibre Toxicology. 9:37.
  • Jalava, PI., Aakko-Saksa, P., Murtonen, T., Happo, MS,. Markkanen, A., Yli-Pirilä, P., Hakulinen, P., Hillamo, R., Mäki-Paakkanen, J., Salonen, RO., Jokiniemi, J., Hirvonen M-R. (2012) Toxicological properties of emission particles from heavy duty engines powered by conventional and bio-based diesel fuels and compressed natural gas. Particle and Fibre Toxicology 9: 37.
  • Karvonen, AM., Hyvärinen, A., Gehring, U., Korppi, M., Doekes, G., Riedler, J., Braun-Fahrländer, C., Bitter, S., Schmid, S., Keski-Nisula, L., Roponen, M., Kaulek, V., Dalphin, J.-C., Pfefferle, P.I., Renz, H., Büchele, G., von Mutius, E., Pekkanen, J., Hirvonen, M.-R., Remes, S., Tiittanen, P., Dalphin, M.-L., Depner, M., Ege, M., Genuneit, J., Illi, S., Kabesch, M., Schaub, B., Weber, J., Frei, R., Lauener, R., Loss, G., Roduit, C. (2012) Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: A birth cohort study in rural areas. Clinical and Experimental Allergy. 42 (8): 1246-1256.
  • Lappalainen, MHJ., Hyvärinen, A., Hirvonen, M-R., Rintala, H., Nevalainen, A., Roponen, M., Pekkanen, J. (2012) High indoor microbial levels are associated with reduced Th1 cytokine secretion capacity in infancy. International Archives of Allergy and Immunology. 159(2):194-203.
  • Loss, G.,  Bitter, S.,   Frei, R., Roduit, R., Lauener, R., Genuneit, J., Pekkanen, J., Hirvonen, M-R., Dalphin, J-C., Dalphin, M-L., Riedler, J., von Mutius, E., Weber, J., Roponen, M., Kabesch, M., Michel, M., Braun-Fahrländer, C., and the PASTURE study group. (2012) Prenatal and early life exposures alter expression of innate immunity genes: The PASTURE cohort study. J Allergy Clin Immunol.(JACI) 130(2): 523-530.
  • Mustonen, K., Keski-Nisula, L., Vaarala, O., Pfefferle, PI., Renz, H., Riedler, J., Dalphin, J.-C., Buechele, G., Lauener, R., Braun-Fahrländer, C., von Mutius, E., Pekkanen, J., Karvonen, A., Roponen, M., Hyvärinen, A., Hirvonen, M.-R., Tiittanen, P., Remes, S., Kaulek, V., Dalphin, M.-L., Ege, M., Depner, M., Weber, J., Schaub, B., Genuneit, J., Kabesch, M., Bitter, S., Loss, G., Roduit, C., Frei, R., Doekes, G. (2012) Few associations between high-sensitivity c-reactive protein and environmental factors in 4.5-year-oldchildren. Pediatric Allergy and Immunology, 23 (6): 522-528.
  • Roduit, C., Frei, R., Loss, G., Büchele, G., Weber, J., Depner, M., Loeliger, S., Dalphin, ML., Roponen, M., Hyvärinen, A., Riedler, J., Dalphin, JC., Pekkanen, J., von Mutius, E., Braun-Fahrländer, C., Lauener, R. and the PASTURE study group (2012) Development of atopic dermatitis according to age of onset and the association with early life exposures. Journal of Allergy Clinical Immunology. 130(1):130-136.
  • Salonen, I., Huttunen, K., Hirvonen, M-R., Dufva, J., Groundström, K., Dufva, H., Pekkanen, J., Salonen, R. (2012) Serum myeloperoxidase is independent of atherosclerosis risk factors. Coron Artery Dis. 23(4): 251-258.
  • Salonen, I., Huttunen, K., Hirvonen, M-R., Dufva, J., Groundström, K., Dufva, H., Pekkanen, J., Salonen, R. (2012) Exhaled nitric oxide and atherosclerosis. Eur. J. Clin.Invest. 42(8): 873-880.
  • Tapanainen, M., Jalava, PI., Mäki-Paakkanen, J., Hakulinen, P., Lamberg, H., Ruusunen, J., Tissari, J., Jokiniemi, J., Hirvonen, M-R. (2012) Efficiency of log food combustion affects the toxicological and chemical properties of emission particles. Toxicological and chemical properties of particles emitted from different log wood combustion appliances. Inhalation Toxicology 24(6): 343-355.
  • Uski, O., Happo, MS., Jalava, PI., Brunner, T., Kelz, T., Obernberger, I., Jokiniemi, J., Hirvonen, M-R. (2012) Acute systemic and lung inflammation in C57Bl/6J mouse after intratracheal instillation of particulate matter from small-scale biomass combustion appliances based on old and modern technologies. Inhalation Toxicology. Inhalation Toxicology. 24: 952-965.

2011

  • Aatamila, M., Verkasalo, P., Korhonen, M., Suominen, L., Hirvonen, M-R., Viluksela, M., Nevalainen, A. (2011) Odour annoyance and physical symptoms among residents living near waste treatment centres. Environmental Research. 111: 164-170.
  • Bomert, M., Köllisch, G., Roponen, M., Lauener, R., Renz, H., Pfefferle, PI., Al-Fakhri, N. (2012) Analytical performance of a multiplexed, bead-based cytokine detection system in small volume samples. Clin Chem Lab Med. 49(10):1691-1693.
  • Lamberg, H., Nuutinen, K., Tissari, J., Ruusunen, J., Pennanen, A.S., Tapanainen, M., Jalava, P.I., Makkonen, U., Hillamo, R., Salonen, R.O., Hirvonen, M.-R., Jokiniemi, J. (2011) Physicochemical characterisation of fine particles from small scale wood combustion for toxicological studies. Atmospheric Environment. 45(40): 7635-7643.
  • Lampi, J., Roponen, M., Hyvärinen, A., Hirvonen, MR., Larsson, L., Nevalainen, A., Pekkanen, J. (2011) Determinants of stimulated peripheral blood cytokine production among farming women. International Journal of Hygiene and Environmental Health. 214(3): 205-209.
  • Roduit, C., Wohlgensinger, J., Frei, R., Bitter, S., Bieli, C., Loeliger, S., Büchele, G., Riedler, J., Dalphin, JC., Remes, S., Roponen, M., Pekkanen, J., Kabesch, M., Schaub, B., von Mutius, E., Braun-Fahrländer, C., Lauener, R.; PASTURE Study Group. (2011) Prenatal animal contact and gene expression of innate immunity receptors at birth are associated with atopic dermatitis. J Allergy Clin Immunol. 127(1): 179-185.
  • Ruusunen, J., Tapanainen, M., Lamberg, H., Nuutinen, K., Tissari, J., Sippula, O., Jalava, PI., Mäki-Paakkanen, J., Hakulinen, P., Pennanen, AS., Salonen, RO., Hillamo, R., Hirvonen, M-R., Jokiniemi, J. (2011) A novel particle sampling system for physicochemical and toxicological characterization of emissions Analytical and Bioanalytical Chemistry. DOI 10.1007/s00216-011-5424-2.
  • Tapanainen, M., Jalava, PI., Mäki-Paakkanen, J., Hakulinen, P., Happo, MS., Lamberg, H., Ruusunen, J., Tissari, J., Nuutinen, K., Yli-Pirilä, P., Hillamo, R., Salonen, R.O., Jokiniemi, J., Hirvonen, M.-R. (2011) In vitro immunotoxic and genotoxic responses induced by fine particle emissions from small-scale wood combustion. Atmospheric Environment. 45(40): 7646-7554.

2010

  • Happo, MS., Hirvonen, M-R., Hälinen, AI., Jalava, PI., Pennanen, AS., Sillanpää, M., Hillamo, R., Salonen, RO. (2010). Seasonal variation in chemical composition of size-segregated urban air particles and the inflammatory activity in the mouse lung. Inhalation Toxicology. 22(1): 17-32.
  • Happo, MS., Salonen, RO., Hälinen, AI., Jalava, PI., Pennanen, AS., Cassee, FR., Gerlofs-Nijland, ME., Dormans, JAMA., Kosma, V-M., Sillanpää, M., Hillamo, R., Hirvonen, M-R. (2010). Inflammation and tissue damage in mouse lung by single and repeated dosing of urban air coarse and fine particles collected from six European cities. Inhalation Toxicology. 22(5): 402-416.
  • Jalava, PI., Salonen, RO., Nuutinen, K., Pennanen, AS., Happo, MS., Penttinen, P., Tissari, J., Frey, A., Hillamo, R., Jokiniemi, J., Hirvonen, M-R. (2010). Effect of combustion condition on cytotoxic and inflammatory activity of residential wood combustion particles. Atmospheric Environment. 44: 1691-1698.
  • Jalava, PI., Tapanainen, M., Kuuspalo, K., Markkanen, A., Hakulinen, P., Happo, MS., Pennanen, AS., Ihalainen, M., Yli-Pirilä, P., Makkonen, U., Teinilä, K., Mäki-Paakkanen, J., Salonen, RO., Jokiniemi, J., Hirvonen, M-R. (2010) Toxicological effects of emission particles from fossil- and biodiesel-fueled diesel engine with and without DOC/POC catalytic converter. Inhalation Toxicology. 22(Suppl.2): 48-58.
  • Keski-Nisula L, Lappalainen MHJ, Mustonen K, Hirvonen M-R, Pfefferle PI, Renz H, Pekkanen J, Roponen M. (2010). Production of interleukin-5, -10 and interferon-γ in cord blood is strongly associated with the season of birth. Clinical and Experimental Allergy 40(11): 1658-1668.
  • Lappalainen MHJ, Huttunen K, Roponen M, Remes S, Hirvonen M-R, Pekkanen J. (2010). Exposure to dogs is associated with a decreased tumour necrosis factor-α –producing capacity in early life. Clinical and Experimental Allergy 40(10): 1498-1506.
  • Rochat, M.K., Ege, M.J., Plabst, D., Steinle, J., Bitter, S., Braun-Fahrländer, C., Dalphin, J.C., Riedler, J., Roponen, M., Hirvonen, M.-R., Büchele, G., Renz, H., Lauener, R., Krauss-Etschmann, S., von Mutius, E.; the PASTURE Study group. (2010). Maternal vitamin D intake during pregnancy increases gene expression of ILT3 and ILT4 in cord blood. Clinical and Experimental Allergy 40(5):786-794.
  • Roponen, M.*, Yerkovich, ST.*, Hollams, E., Sly, P.D., Holt, P.G., Upham, J.W. (2010). Reduced expression of an anti-viral protein following Toll-like receptor 7 stimulation in adolescents with asthma. European Respiratory Journal 35(1):64-71. *These authors contributed equally to this work.

 

2009

  • Jalava, PI., Hirvonen, M-R., Sillanpää, M., Pennanen, AS., Happo, MS., Hillamo, R., Cassee, FR., Gerlofs-Nijland, M., Borm PJA., Schins, RPF., Janssen, NAH., Salonen, RO. (2009). Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line. Inhalation Toxicology. 21:994-1006.
  • Karvonen, A.M., Hyvärinen, A., Roponen, M., Hoffmann, M., Korppi, M., Remes, S., von Mutius, E., Nevalainen, A., Pekkanen, J. (2009). Confirmed moisture damage at home, respiratory symptoms and atopy in early life: a birth-cohort study. Pediatrics. 124(2):e329-338.
  • Karvonen, A., Hyvärinen, A., Roponen, M., Korppi, M., Remes, S., von Mutius, E., Nevalainen, A., Pekkanen, J. (2009). Indoor moisture damage and respiratory symptoms and atopy in early life: a birth cohort study with home inspections. Pediatrics 124(2):e329-38.
  • Lappalainen, MHJ., Roponen, M., Pekkanen, J., Huttunen, K., Hirvonen, M-R.  (2009). Maturation of cytokine producing capacity from birth to one year of age.   Pediatric allergy and immunology. 20: 714-725.
  • Lappalainen M, Roponen M, Pekkanen J, Huttunen K, Hirvonen M-R. (2009). Maturation of cytokine –producing capacity from birth to 1 yr of age. Pediatric Allergy and Immunology 20(8): 714-725.
  • Markkanen (Penttinen), P., Pelkonen, J., Tapanainen, M., Mäki-Paakkanen, J., Jalava. P., Hirvonen, M-R. (2009). Co-cultivated damp building related microbes Streptomyces californicus and Stachybotrys chartarum induce immunotoxic and genotoxic responses via oxidative stress. Inhalation Toxicology. 21(10): 857-867.
  • Pfefferle, PI., Büchele, G., Blümer, N., Roponen, M., Ege, M.J., Krauss-Etschmann, S., Genuneit, J., Hyvärinen, A., Hirvonen, M.-R., Lauener, R., Pekkanen, J., Riedler, J., Dalphin, J.C., Brunekeef, B., Braun-Fahrländer, C., von Mutius, E. Renz, H.: on behalf of the PASTURE Study group. (2010). Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: The PASTURE-Study. Journal of Allergy and Clinical Immunology 125(1):108-115.e1-3.
  • Roponen, M., Yerkovich, S.T., Hollams, E., Sly, P.D., Holt, P.G., Upham, J.W. (2009). Toll-like receptor 7 function is reduced in adolescents with asthma. European Respiratory Journal. 35(1):64-71.
  • Tampio, M., Markkanen, P., Puttonen, K., Hagelberg, E., Heikkinen, H.., Loikkanen, J. Hirvonen, M-R., Väkäkangas, KH. (2009). Induction of PUMA-alpha and down-regulation of PUMA-beta expression is associated with benzo(a)pyrene-induced apoptosis in MCF-7 cells. Toxicology letters. 188: 152-159.
  • Sudre, B., Vacheyrou, M., Braun-Fahrländer, C., Normand, A.C., Waser, M., Reboux, G., Ruffaldi, P., von Mutius, E., Piarroux, R.; PASTURE study group.(2009). High levels of grass pollen inside European dairy farms: a role for the allergy-protective effects of environment? Allergy 64(7):1068-73.
  • van den Biggelaar, A.H., Prescott, S.L., Roponen, M., Nadal-Sims, M.A., Devitt, C.J., Phuanukoonnon, S., Pomat, W., Tulic, M.K., Lehmann, D., Siba, P.M., Richmond, P.C., Holt, P.G. (2009). Neonatal innate cytokine responses to BCG controlling T-cell development vary between populations. Journal of Allergy and Clinical Immunology. 124(3):544-550.
  • Yerkovich, S.T., Roponen, M., Smith, M.E., McKenna, K., Bosco, A., Subrata, L.S., Mamessier, E., Wikström, M.E., Le Souef, P., Sly, P.D., Holt, P.G., Upham, J.W. (2009). Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a TH2-skewed immune response. Journal of Allergy and Clinical Immunology. 123(1):209-216.

 

2008

  • Ege, M.J., Herzum, I., Büchele, G., Krauss-Etschmann, S., Lauener, R.P., Bitter, S., Roponen, M., Remes, S., Vuitton, D.A., Riedler, J., Brunekreef, B., Dalphin, J.C., Braun-Fahrländer, C., Pekkanen, J., Renz, H., von Mutius, E.; PASTURE Study Group. (2008). Specific IgE to allergens in cord blood is associated with maternal immunity to Toxoplasma gondii and rubella virus. Allergy. 63(11):1505-1511.
  • Ege, M.J., Herzum, I., Büchele, G., Krauss-Etschmann, S., Lauener, R.P., Roponen, M., Hyvärinen, A., Vuitton, D.A., Riedler, J., Brunekreef, B., Dalphin, J.C., Braun-Fahrländer, C., Pekkanen, J., Renz, H., von Mutius, E.; Protection Against Allergy Study in Rural Environments (PASTURE) Study group. (2008). Prenatal exposure to a farm environment modifies atopic sensitization at birth. Journal of Allergy and Clinical Immunology. 122(2):407-412.
  • Gehring U, Spithoven J, Schmid S, Bitter S, Braun-Fahrländer C, Dalphin JC, Hyvärinen A, Pekkanen J, Riedler J, Weiland SK, Büchele G, von Mutius E, Vuitton DA, Brunekreef B; PASTURE study group. (2008). Endotoxin levels in cow's milk samples from farming and non-farming families - the PASTURE study. Environment International 34(8):1132-6.
  • Happo, MS., Hirvonen, M-R., Hälinen, AI., Jalava, PI., Pennanen, AS., Sillanpää, M., Hillamo, R., Salonen, RO. (2008). Chemical compositions responsible for inflammation and tissue damage in the mouse lung by coarse and fine particulate samples from contrasting air pollution in Europe. Inhalation Toxicology. 20:1–17.
  • Huttunen, K., Rintala, H., Hirvonen, M-R., Vepsäläinen, A., Hyvärinen, A., Meklin, T., Toivola, M., Nevalainen, A. (2008). Indoor air particles and bioaerosols before and after renovation of moisture damaged building: Effect on the biological activity and microbial flora. Environmental Research. 107(3):291-298.
  • Jalava, PI., Salonen, RO., Pennanen, AS., Sillanpää, M., Hälinen, AI., Happo, MS., Hillamo, R., Brunekreef, B., Katsouyanni, K., Sunyer, J., Hirvonen, M-R. (2008). Effects of solubility of urban air fine and coarse particulate samples on cytotoxic and inflammatory responses in RAW 264.7 macrophage cell line. Toxicology and Applied Pharmacology.  229(2):146-160.
  • Kaarakainen, P., Meklin, T., Hyvärinen, A., Rintala, H., Kärkkäinen, P., Vepsäläinen, A., Hirvonen, M-R., Nevalainen, A. (2008). Seasonal variation in airborne microbial concentrations and diversity at a landfill, urban and rural site. CLEAN - Soil, Air, Water. 36(7):556-563.
  • Lappalainen, MHJ., Roponen, M., Hyvärinen, A., Nevalainen, A., Laine, O., Pekkanen, J., Hirvonen, M-R. (2008). Exposure to environmental bacteria may have differing effects on TNF-α and IL-6 producing capacity in infancy. Clinical & Experimental Allergy. 38:1483-1492.
  • Lappalainen MHJ, Roponen M, Hyvärinen A, Nevalainen A, Laine O, Pekkanen J, Hirvonen M-R. (2008). Exposure to environmental bacteria may have differing effects on tumour necrosis factor -α and interleukin-6 –producing capacity in infancy. Clinical and Experimental Allergy 38(9):1483-1492.
  • Mättö, M., Pietilä, A-R., Postila, V., Huttunen, K., Hirvonen, M-R., Pelkonen, J. (2008). Induction of inflammatory response by B-lymphocytes.  Scandinavian Journal of Immunology. 67(3):209-217.
  • Pfefferle, P., Serdar, S., Krauss-Etschmann, S., Herzum, I., Christoph, E., Lauener, RP., Roponen, M., Hirvonen, M-R., Vuitton, D., Riedlers, J., Brunekreef, B., Dalphin, J-C., Braun-Fahrländer, C., Pekkanen, J., von Mutius, E., Renz, H., and the Pasture Study Group. (2008). Cord blood allergen-specific  IgE is associated with reduced IFN- γ production by cord blood cells - The PASTURE study. Journal of Allergy and Clinical Immunology. 122(4):711-716.
  • Tissari, J., Frey, A., Lyyränen, J., Hytönen, K., Sippula, K., Saarnio, K., Tapper, U., Pennanen, A., Hillamo, R., Salonen, RO., Hirvonen, M-R, Jokiniemi, J. (2008) Fine particle and gaseous  emissions from normal and  smouldering wood combustion fired in a conventional masonry heater. Atmospheric Environment. 42(34):7862-7873.
  • Yli-Pirilä, T., Kusnetsov, J., Hirvonen, M-R., Seuri, M., Nevalainen, A. (2008). Survival of amoebae on building materials. Indoor Air. 19(2):113-121.

2007

  • Happo, MS., Salonen, RO., Hälinen, AI., Jalava, PI., Pennanen, AS., Kosma, V-M., Sillanpää, M., Hillamo R., Brunekreef, B., Katsouyanni, K., Sunyer, J., Hirvonen, M-R. (2007).  Dose and time dependency of inflammatory responses in the mouse lung to urban air coarse, fine and ultrafine particles from six European cities. Inhalation Toxicology. 19(3):227-246.
  • Jalava, PI., Salonen, RO., Pennanen, AS., Sillanpää, M., Hälinen, AI., Happo, MS., Hillamo, R., Brunekreef, B., Katsouyanni, K., Sunyer, J., Hirvonen, M-R. (2007). Heterogeneities in inflammatory and cytotoxic responses of macrophages to urban air coarse, fine and ultrafine particles from six European sampling campaigns. Inhalation Toxicology. 19(3):213-255.
  • Kontro, MH., Lignell, U., Hyvärinen, A., Vahteristo, M., Hirvonen, M-R., Nevalainen, A. (2007). Nutrient effects on ten Streptomyces spp. Sporulation. Communicating current research and educational topics and trends in applied Microbiology. A.Mendez-Vilas (Ed.) 137-142.
  • Penttinen, P., Tampio, M., Mäki-Paakkanen, J., Vähäkangas, K., Pelkonen, J., Hirvonen, M.-R. (2007). DNA damage and p53 in RAW264.7 cells induced by the spores of co-cultivated Streptomyces californicus and Stachybotrys chartarum. Toxicology. 235:92-102.
  • Yli-Pirilä, T., Huttunen, K., Nevalainen, A., Hirvonen, M-R. (2007). Effects of co-culture of amoebae with indoor microbes on their cytotoxicity and inflammatory potential. Environmental Toxicology, 22:357-367.

2006

  • Hyvärinen A, Roponen M, Tiittanen P, Laitinen S, Nevalainen A, Pekkanen J. (2006). Dust sampling methods for endotoxin - an essential, but underestimated issue. Indoor Air 16(1):20-7.
  • Jalava, PI., Salonen, RO., Hälinen, AI., Penttinen, P., Pennanen, A., Sillanpää, M., Sandell, E., Hillamo, R., Hirvonen, M-R. (2006). In-vitro inflammatory and cytotoxic effects of size-segregated particulate samples collected during long-range transport of wildfire smoke to Helsinki. Toxicology and Applied Pharmacology. 215(3):341-353. 
  • Penttinen, P., Pelkonen, J., Huttunen, K., Hirvonen, M-R. (2006). Co-cultivation of Streptomyces californicus and Stachybotrys chartarum stimulates the production of cytostatic compound(s) with immunotoxic properties. Toxicology and Applied Pharmacology. 217:342-351.
  • Stark, H., Roponen, M., Purokivi, M., Randell, J., Tukiainen, H., Hirvonen, M-R. (2006). Aspergillus fumigatus challenge increases cytokine levels in nasal lavage fluid. Inhalation Toxicology. 18(13):1033-1039.
  • Tuomainen, A., Stark, H., Seuri, M., Hirvonen, M-R., Linnainmaa, M., Sieppi, M., Tukiainen, H. (2006). Experimental PVC flooring material challenge in subjects with occupational PVC exposure. Environmental Health Perspectives. 114:1409-1413.
  • Yli-Pirilä, T., Kusnetsov, J., Hirvonen, M-R., Seuri, M., Nevalainen, A. (2006) Effects of amoebae on the growth of moldy building microbes. Canadian Journal of Microbiology. 52(4):383-390.

 

2005

  • Hirvonen, M-R., Huttunen, K., Roponen, M. (2005). Bacterial strains from moldy buildings are highly potent inducers of inflammatory and cytotoxic effects. Indoor Air 15(9): 65-70.
  • Jalava, P., Salonen, RO., Hälinen, AI., Sillanpää, M., Hirvonen, M-R. (2005) Effects of sample preparation on chemistry, cytotoxicity and inflammatory responses induced by air particulate matter. Inhalation Toxicology. 17(2):107-118.
  • Kontro (Suutari), M., Lingnell, U., Hirvonen, M-R., Nevalainen, A. (2005).  pH effects on ten Streptomyces spp growth and sporulation depend on nutritents . Letters in Applied Microbiology Letters in Applied Microbiology. 41(1):32-38.
  • Korhonen HT, Happo M, Rekila T, Valaja J, Polonen I. Effects of diet calcium: phosphorus ratio and metabolizable energy content on development of osteochondrosis, foot bending and performance in blue foxes. Animal Science. 80: 325-331 Part 3, Jun 2005.
  • Lignell, U., Meklin, T., Putus, T., Vepsäläinen, A., Roponen, M., Torvinen, E., Reeslev, M., Pennanen, S., Hirvonen M-R., Kalliokoski, P., Nevalainen, A. (2005). Microbial exposure, symptoms and inflammatory mediators in nasal lavage fluid of kitchen and clerical personnel in schools. International journal of occupational medicine and environmental health. 18(2):139-150.
  • Meklin, T., Putus, T., Pekkanen, J., Hyvärinen, A., Hirvonen, M-R., Nevalainen, A. (2005). The effects of moisture-damage repairs on microbial exposure and symptoms in schoolchildren. Indoor Air. 15(10):40-47.
  • Murtoniemi, T., Penttinen, P., Nevalainen, A., Hirvonen, M-R. (2005). Effects of microbial co-cultivation on bioactivity of spores. Inhalation Toxicology. 17:681-693.
  • Penttinen, P., Pelkonen, J., Huttunen, K., Toivola, M., Hirvonen, M-R. (2005). Interactions between Streptomyces californicus and Stachybotrys chartarum induce apoptosis and cell cycle arrest in mouse macrophages. Toxicology and Applied Pharmacology. 202:278-288.
  • Penttinen, P., Huttunen, K., Pelkonen, J. Hirvonen, M-R. (2005). Simultaneus exposure to different proportions of Streptomyces californicus and Stachybotrys chartarum affects differently to inflammatory responses in mouse macrophages. Inhalation Toxicology. 17(2):79-86.
  • Roponen, M., Hyvärinen, A., Hirvonen, M-R., Keski-Nisula, L., Pekkanen, J. (2005). Change in interferon gamma producing capacity in early life and exposure to environmental microbes. Journal of Allergy and Clinical Immunology. 116(5):1048-1052.
  • Seuri, M., Paldanius, M., Leinonen, M., Roponen, M., Hirvonen, M-R., Saikku, P. (2005). Chlamydia pneumoniae antibodies in office workers with and without inflammatory rheumatic diseases in a moisture–damaged building. European Journal of Clinical Microbiology & Infectious Diseases. 24:236-237.
  • Stark, H., Randell, J., Hirvonen, M-R., Roponen, M., Purokivi, M., Tukiainen, H. (2005). The effects of Aspergillus fumigatus exposure on exhaled and nasal NO levels. European Respiratory Journal. 26(5):887-893.

2004

  • Harvima, IT., Lappalainen, K., Hirvonen, M-R., Mättö, M., Kivinen, PK., Hyttinen, M., Pelkonen,  I.,  Naukkarinen, A. (2004). Heparin modulates the growth and adherence and augments the growth-inhibitory action of TNF-α on cultured human keratinocytes. Journal of Cellular Biochemistry. 15:92(2):372-86.
  • Holopainen,  M., Hirvonen, M-R., Komulainen, H., Klockars, M. (2004). Effect of the shape of mica particles on the production of tumor necrosis factor alpha in mouse macrophages. Scandinavian Journal of Work, Environment & Health. 30(2):91-98.
  • Huttunen, K., Nielsen, KF., Jussila, J., Hirvonen, M-R. (2004). Additive interaction in simultaneous exposure to Streptomyces californicus and Stachybotrys chartarum -search of active component. Environmental Health Perspectives. 112:659-665.
  • Keski-Nisula, L., Hirvonen, M-R., Roponen, M., Heinonen, S., Pekkanen, J. (2004). Spontaneus and stimulated interleukin-6 and tumor necrosis factor-alpha production at delivery and three months after birth. European Cytokine Network. 15(1):67-72.
  • Keski-Nisula, L., Roponen, M. Hirvonen, M-R., Heinonen, S., Pekkanen, J. (2004). Stimulated cytokine production correlates in umbilical arterial and venous blood at delivery. European Cytokine Network. 15(4):347-352.
  • Pylkkänen, L., Gullstén, H., Majuri, M-L., Andersson, U., Vanhala, E.,  Meklin, T., Hirvonen, M-R., Alenius, H. Savolainen, K. (2004). Exposure to Aspergillus fumigatus spores induces chemokine expression in mouse macrophages. Immunotoxicology Section of Toxicology. 2004(2-3):255-263.
  • Salonen, RO., Hälinen, AI., Pennanen, AS., Hirvonen, M-R., Sillanpää, MK., Hillamo, RE., Shi, T., Borm, P., Sandell, E., Koskentalo, T., Aarnio, P. (2004). Chemical and in-vitro toxicological characteristics of winter and spring PM10 in Helsinki, Finland. Scandinavian Journal of Work, Environment & Health. 30(2):80-90.
  • Yli-Pirilä, T.,  Kusnetsov, J., Haatainen, S., Hänninen, M., Jalava, P.,  Reiman, M., Seuri, M., Hirvonen, M-R., Nevalainen, A. (2004). Amoebae and other protozoa in material samples from moisture damaged buildings. Environmental Research. 96(3):250-256.